HJNO Sep/Oct 2023

CTE 24 SEP / OCT 2023 I  HEALTHCARE JOURNAL OF NEW ORLEANS Informant-reported concussion number not associated with CTE status, CTE severity, or neurofibrillary tangle burden Across all brain donors, there was no association between informant-reported concussion number and CTE status (Table 4). For athletes with CTE, there was no asso- ciation between informant-reported con- cussion number and CTE severity (Table 5). There was no association between infor- mant-reported concussion number and cumulative neurofibrillary tangle (NFT) burden (mean difference in NFT burden index per concussion; Table 6). All esti- mates above were adjusted for age at death (models unadjusted for age are included in Supplementary Tables 1–3). Position at highest level not associated with CTE status, CTE severity, or neurofibrillary tangle burden Across a range of analyses, primary playing position had no meaningful asso- ciation with CTE related outcomes. We observed no association between football position played at the highest level and CTE status with positions evaluated individually (Supplementary Table 4) or dichotomously (Table 4). For those athletes with CTE, there was no association between position played at the highest level and CTE severity (Supplemen- tary Table 4, Table 6). There was no associa- tion between position played at the highest