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the way a person uses it. In other words, it is not only the drink, but also the drinker, as illustrated by the following dialogue in Shakespeare’s Othello (Act 2, Scene 3): Cas- sio—“O thou invisible spirit of wine, if thou hast no name to be known by, let us call thee devil” … Iago—“Come, come. Good wine is a good familiar creature, if it be well used.” The etiological complexity of addiction is illustrated by a history of pendulum swings of social and medical opinion. There is no resting equilibrium on unanimous beliefs. It has been common to observe, at the same time and in the same place, the confronta- tion of opposing attitudes on issues such as: strict vs broad definition of addiction (eg including gambling or not); laissez-faire or prohibition; punishing or treating the addict; and individual responsibility. n REFERENCES 1. Vetulani J. Drug addiction. Part I. Psychoactive substances in the past and present. Pol J Pharmacol. 2001;53:201–214. 2. Frank JW, Moore RS, Ames GM. 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